Hemicorea induced by nonketotic hyperglycemia: clinical-radiological discordance
##plugins.themes.bootstrap3.article.details##
Hemicorea induced by nonketotic hyperglycemia is a rare complication of diabetes mellitus. It is characterized by the triad of unilateral involuntary choreiform movements, hyperglycemia without ketosis, and hyperintensity of contralateral basal ganglia on nuclear magnetic resonance images mainly on T1 or high density on CT scan. It has a high potential for total or partial recoverability of its clinical expression, for this reason timely diagnosis and treatment is essential to avoid irreversible neurological sequelae. Two clinical cases of this syndrome are presented, in which the inconsistency of the imaging findings with the clinical ones is striking.
Chorea, Diabetes Mellitus, Basal ganglia, Hyperglycemia, Nuclear magnetic resonanceCorea, Diabetes mellitus, Ganglios basales, Hiperglucemia, Resonancia magnética nuclear
1. Pham K, Meegada S, Challa T, Peddi P, Annakula M. Hemichorea Induced by Non-ketotic Hyperglycemia in a Caucasian Woman. 2020;12(2).
2. Lin JB, Sng AA, Wang FS, Tan AP, Han VX. Acute hemichorea in a young type 1 diabetic. Int J Neurosci. 2019;0(0):1–3.
3. Ryan C, Ahlskog JE, Savica R. Hyperglycemic chorea/ballism ascertained over 15 years at a referral medical center. Park Relat Disord. 2018;48:97–100.
4. Zheng W, Chen L, Chen JH, Lin X, Tang Y, Lin XJ, et al. Hemichorea Associated With Non-ketotic Hyperglycemia: A Case Report and Literature Review. Front Neurol. 2020;11:1–6.
5. Guerra M, Gonçalo S, Daniela M, Jorge F, Armando C. Hyperglycaemic Hemichorea and Hyperglycaemic Hyperosmolar Syndrome in a Patient with HbA1c levels of 19.9%: A Rare and Potentially Reversible Case. Eur Journalof Case Reports inInternal Med. 2019;7.
6. Oh SH, Lee KY, Im JH, Lee MS. Chorea associated with non-ketotic hyperglycemia and hyperintensity basal ganglia lesion on T1-weighted brain MRI studya meta-analysis of 53 cases including four present cases. J Neurol Sci. 2002;200(1–2):57–62.
7. Chua CB, Sun CK, Hsu CW, Tai YC, Liang CY, Tsai IT. “Diabetic striatopathy”: clinical presentations, controversy, pathogenesis, treatments, and outcomes. Sci Rep. 2020;10(1):1–11.
8. Doher N, Gupta H V. DaT Scan “Abnormality” in Hyperglycemic-Hemichorea. Tremor Other Hyperkinet Mov (N Y). 2019;9:4–6.
9. Fong SL, Tan AH, Lau KF, Ramli N, Lim S-Y. Hyperglycemia-Associated Hemichorea-Hemiballismus with Predominant Ipsilateral Putaminal Abnormality on Neuroimaging. J Mov Disord. 2019;12(3):187–9.
10. Özgür A, Esen K, Kaleağası H, Yılmaz A, Kara E. Diabetic striatopathy in a patient with hemiballism. Emerg Radiol. 2015;22(3):347–9.

This work is licensed under a Creative Commons Attribution 4.0 International License.