maternal-fetal chikungunya infection associated with neonatal myocarditis
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Chikungunya is an arbovirus of the Togaviridae family first isolated in Tanzania and Uganda in 1953. This infection has been developed with endemic and is transmitted by the Aedes mosquito. The mechanism of transmission from mother to child is not yet clear, but it has identified potential complications from vertical transmission, such as birth defects, stillbirths, intrauterine growth retardation and preterm deliveries. Then two cases of infants who developed cardiac arrhythmias in their first days of life, children of mothers with febrile syndrome in progress by Chikungunya are presented. Myocarditis vertical transmission Chikungunya and confirmed by polymerase chain reaction was diagnosed. Both patients received medical management including immunoglobulins, with clinical improvement without complications or dead.
Chikungunya arbovirus, newborn, pregnancy, Maternal-Fetal Exchangechikunguña, arbovirus, recién nacido, embarazo, exposición transplacentaria.
2. Gérardin P, Barau G, Michault A, Bintner M, Randrianaivo H, Choker G, et al. Multidisciplinary prospective study of mother-to-child chikungunya virus infections on the island of La Réunion. PLoS Med. 2008;5(3):0413–23.
3. Laoprasopwattana K, Suntharasaj T, Petmanee P, Suddeaugrai O, Geater a. Chikungunya and dengue virus infections during pregnancy: seroprevalence, seroincidence and maternal–fetal transmission, southern Thailand, 2009–2010. Epidemiol Infect [Internet]. 2015;1–8. Available from: http://www.journals.cambridge.org/abstract_S0950268815001065
4. Gérardin P, Sampériz S, Ramful D, Boumahni B, Bintner M, Alessandri JL, et al. Neurocognitive Outcome of Children Exposed to Perinatal Mother-to-Child Chikungunya Virus Infection: The CHIMERE Cohort Study on Reunion Island. PLoS Negl Trop Dis. 2014;8(7).
5. Shrivastava A, Waqar Beg M, Gujrati C, Gopalan N, Rao PVL. Management of a vertically transmitted neonatal Chikungunya thrombocytopenia. Indian J Pediatr. 2011;78(8):1008–9.
6. Ramful D, Carbonnier M, Pasquet M, Bouhmani B, Ghazouani J, Noormahomed T, et al. Mother-to-child transmission of Chikungunya virus infection. Pediatr Infect Dis J. 2007;26(9):811–5.
7. Ramful D, Samperiz S, Fritel X, Michault a., Jaffar-Bandjee M-C, Rollot O, et al. Antibody Kinetics in Infants Exposed to Chikungunya Virus Infection During Pregnancy Reveals Absence of Congenital Infection. J Infect Dis [Internet]. 2014;209(11):1726–30. Available from: http://jid.oxfordjournals.org/lookup/doi/10.1093/infdis/jit814
8. Pollack A, Kontorovich AR, Fuster V, Dec GW. Viral myocarditis—diagnosis, treatment options, and current controversies. Nat Rev Cardiol [Internet]. 2015;1–12. Available from: http://www.nature.com/doifinder/10.1038/nrcardio.2015.108
9. Durani Y, Giordano K, Goudie BW. Myocarditis and pericarditis in children. Pediatr Clin North Am [Internet]. Elsevier Ltd; 2010;57(6):1281–303. Available from: http://dx.doi.org/10.1016/j.pcl.2010.09.012
10. Article R. Chikungunya Virus and the Global Spread of a Mosquito-Borne Disease. 2015;
11. Fritel X, Rollot O, Gérardin P, Gaüzère BA, Bideault J, Lagarde L, et al. Chikungunya virus infection during pregnancy, Réunion, France, 2006. Emerg Infect Dis. 2010;16(3):418–25.
12. Nelly B, Jaramillo R. Infección por el virus del Chikungunya. 2014;28(2):313–23.