Cryptococcosis: A Cause of Adrenal Insufficiency. A Case Report and Literature Review
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Jun 3, 2015
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Abstract
Cryptococcosis is a systemic fungal infection caused by the Cryptococcus encapsulated yeast. It is acquired through inhalation of contagious particles (basidiospores), causing a primary pulmonary infection (frequently asymptomatic). Then, it may disseminate to any organ, usually in immunosuppressed patients, with a wide variety of clinical manifestations, including adrenal insufficiency. Disseminated cryptococcosis preferentially affects the CNS, causing meningoencephalitis, a lethal process if untreated. We present a case of a 61-year-old HIV negative male with adrenal insufficiency caused by disseminated cryptococcosis.
Keywords
criptococosis, micosis, insuficiencia adrenal, cryptococcosis, mycoses, adrenal insufficiency,
References
1. Chayakulkeeree M, Perfect JR. Cryptococcosis. Infect Dis Clin North Am. 2006;20(3):507-44, v-vi.
2. Perfect JR, Casadevall A. Cryptococcosis. Infect Dis Clin North Am. 2002;16(4):837-74, v-vi.
3. Negroni R. Cryptococcosis. Clin Dermatol. 2012;30(6):599-609.
4. Srikanta D, Santiago-tirado FH, Doering TL. Cryptococcus neoformans: historical curiosity to modern pathogen. Yeast. 2014;31(2):47-60.
5. Bovers M, Hagen F, Boekhout T. Diversity of the Cryptococcus neoformans-Cryptococcus gattii species complex. Rev Iberoam Micol. 2008;25(1):S4-12.
6. Kwon-chung KJ, Varma A. Do major species concepts support one, two or more species within Cryptococcus neoformans? FEMS Yeast Res. 2006;6(4):574-87.
7. Lindell RM, Hartman TE, Nadrous HF, Ryu JH. Pulmonary cryptococcosis: CT findings in immunocompetent patients. Radiology. 2005;236(1):326-31.
8. Zinck SE, Leung AN, Frost M, Berry GJ, Müller NL. Pulmonary cryptococcosis: CT and pathologic findings. J Comput Assist Tomogr. 2002;26(3):330-4.
9. Wu B, Liu H, Huang J, Zhang W, Zhang T. Pulmonary cryptococcosis in non-AIDS patients. Clin Invest Med. 2009;32(1):E70-7.
10. Charmandari E, Nicolaides NC, Chrousos GP. Adrenal insufficiency. Lancet. 2014;383(9935):2152-67.
11. Oelkers W. Adrenal insufficiency. N Engl J Med. 1996;335(16):1206-12.
2. Perfect JR, Casadevall A. Cryptococcosis. Infect Dis Clin North Am. 2002;16(4):837-74, v-vi.
3. Negroni R. Cryptococcosis. Clin Dermatol. 2012;30(6):599-609.
4. Srikanta D, Santiago-tirado FH, Doering TL. Cryptococcus neoformans: historical curiosity to modern pathogen. Yeast. 2014;31(2):47-60.
5. Bovers M, Hagen F, Boekhout T. Diversity of the Cryptococcus neoformans-Cryptococcus gattii species complex. Rev Iberoam Micol. 2008;25(1):S4-12.
6. Kwon-chung KJ, Varma A. Do major species concepts support one, two or more species within Cryptococcus neoformans? FEMS Yeast Res. 2006;6(4):574-87.
7. Lindell RM, Hartman TE, Nadrous HF, Ryu JH. Pulmonary cryptococcosis: CT findings in immunocompetent patients. Radiology. 2005;236(1):326-31.
8. Zinck SE, Leung AN, Frost M, Berry GJ, Müller NL. Pulmonary cryptococcosis: CT and pathologic findings. J Comput Assist Tomogr. 2002;26(3):330-4.
9. Wu B, Liu H, Huang J, Zhang W, Zhang T. Pulmonary cryptococcosis in non-AIDS patients. Clin Invest Med. 2009;32(1):E70-7.
10. Charmandari E, Nicolaides NC, Chrousos GP. Adrenal insufficiency. Lancet. 2014;383(9935):2152-67.
11. Oelkers W. Adrenal insufficiency. N Engl J Med. 1996;335(16):1206-12.
How to Cite
Salcedo, J. D., Vera, C. A., & Jaramillo García, L. F. (2015). Cryptococcosis: A Cause of Adrenal Insufficiency. A Case Report and Literature Review. Universitas Medica, 56(4), 460–469. https://doi.org/10.11144/Javeriana.umed56-4.ccia
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Case Reports